2758436-98-3
2758436-98-3
Chemical Structure
EGFR-IN-112
- No. CAS: 2758436-98-3
- Formula:C27H23N3S
- Molecular Weight:421.56
InChIKey: BRLRIGFPXOEBQR-UHFFFAOYSA-N
SMILES: C1(C2=CC=CC=C2)=NN=C(C3=CC=CC=C3)C4=C1C(C5=CSC=C5)=NC64CCCCC6
Biological Activity: EGFR-IN-112 (SPP10) is an EGFR kinase inhibitor which exhibits IC50s of 2.31 ± 0.3, 3.16 ± 0.8, and 4.2 ± 0.2 μM, against MCF-7, H69AR, and PC-3 cancer cells, respectively. EGFR-IN-112 also demonstrates selective cytotoxicity against cancer cells[1].
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EGFR-IN-112 | EGFR-IN-112 (SPP10) is an EGFR kinase inhibitor which exhibits IC50s of 2.31 ± 0.3, 3.16 ± 0.8, and 4.2 ± 0.2 μM, against MCF-7, H69AR, and PC-3 cancer cells, respectively. EGFR-IN-112 also demonstrates selective cytotoxicity against cancer cells. | |||||||||||||||||||||
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