2762279-02-5
Chemical Structure
ZDLD20
- CAS No.: 2762279-02-5
- Formula:C22H22N6O
- Molecular Weight:386.45
IUPAC Name: N-(5-(4-methylpiperazin-1-yl)pyridin-2-yl)-9H-pyrido[3,4-b]indole-1-carboxamide
InChIKey: KNMQEDYCAKYYTK-UHFFFAOYSA-N
SMILES: O=C(C1=NC=CC2=C1NC3=C2C=CC=C3)NC4=NC=C(N5CCN(C)CC5)C=C4
Biological Activity: ZDLD20, a β-carboline, is orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 6.51 μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ZDLD20 | 99.84% | ZDLD20, a β-carboline, is orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 6.51 μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity. | ||||||||||||||||||||
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Keywords
