1. Cell Cycle/DNA Damage
  2. CDK
  3. ZDLD20

ZDLD20 

Cat. No.: HY-115909
Handling Instructions

ZDLD20, a β-carboline, is orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 6.51  μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity.

For research use only. We do not sell to patients.

ZDLD20 Chemical Structure

ZDLD20 Chemical Structure

CAS No. : 2762279-02-5

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Description

ZDLD20, a β-carboline, is orally active and selective CDK4/CycD3 inhibitor with an IC50 value of 6.51  μM. ZDLD20 exhibits potent anti-HCT116 activity including inhibition of colony formation, inhibition of invasion and migration, inducing of apoptosis, and arresting of G1 phase in cell cycle. ZDLD20 exhibits potent anticancer activity[1].

IC50 & Target[1]

CDK4/CycD3

6.51  μM (IC50)

Molecular Weight

386.45

Formula

C22H22N6O

CAS No.
SMILES

O=C(C1=NC=CC2=C1NC3=C2C=CC=C3)NC4=NC=C(N5CCN(C)CC5)C=C4

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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ZDLD20
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HY-115909
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