2768759-52-8
Chemical Structure
PD-1/PD-L1-IN-25
- CAS No.: 2768759-52-8
- Formula:C26H24ClN3O5
- Molecular Weight:493.94
IUPAC Name: (S)-1-((6-(2-chloro-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)benzamido)pyridin-3-yl)methyl)pyrrolidine-3-carboxylic acid
InChIKey: IFRDLUIKBRLJIE-SFHVURJKSA-N
SMILES: O=C(C1=C(C(C2=CC3=C(OCCO3)C=C2)=CC=C1)Cl)NC4=NC=C(C=C4)CN5CC[C@@H](C5)C(O)=O
Biological Activity: PD-1/PD-L1-IN-25 (compound D2) is an inhibitor of PD-1/PD-L1 interaction with an IC50 value of 16.17 nM. PD-1/PD-L1-IN-25 activates the antitumor immunity of T cells efficiently in PBMCs. PD-1/PD-L1-IN-25 can be used for the research of cancer[1].
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PD-1/PD-L1-IN-25 | PD-1/PD-L1-IN-25 (compound D2) is an inhibitor of PD-1/PD-L1 interaction with an IC50 value of 16.17 nM. PD-1/PD-L1-IN-25 activates the antitumor immunity of T cells efficiently in PBMCs. PD-1/PD-L1-IN-25 can be used for the research of cancer. | |||||||||||||||||||||
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Keywords
