2770246-75-6
2770246-75-6
Chemical Structure
HSD17B13-IN-51
- CAS No.: 2770246-75-6
- Formula:C22H13Cl2F3N4O3
- Molecular Weight:509.26
InChIKey: KYPBLQVDALJCDL-UHFFFAOYSA-N
SMILES: O=C(C1=CC(Cl)=C(C(Cl)=C1)O)NC2=CC=CC(N=CN3CC4=CC=CN=C4C(F)(F)F)=C2C3=O
Biological Activity: HSD17B13-IN-51 (Compound 82) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-51 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI)[1].
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HSD17B13-IN-51 | HSD17B13-IN-51 (Compound 82) is an inhibitor of hydroxysteroid 17β-dehydrogenase 13 (HSD17B13) with an IC50 value of ≤ 0.1 μM for estradiol. HSD17B13-IN-51 can be used for research on liver diseases, metabolic diseases, or cardiovascular diseases, such as NAFLD or NASH, as well as drug-induced liver injury (DILI). | |||||||||||||||||||||
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References
Keywords
