2781135-27-9
2781135-27-9
Chemical Structure
DPP-1-IN-1
- CAS. Nr.: 2781135-27-9
- Formula:C23H21FN4O3
- Molecular Weight:420.44
InChIKey: AEHYRYFFWZDTDE-JTSKRJEESA-N
SMILES: O=C(N[C@@H](CC1=C(F)C=C(C(C=CC(C#N)=C2)=C2CO3)C3=C1)C#N)[C@@H]4CNCCCO4
Biological Activity: DPP-1-IN-1 (Compound 14) is an orally active inhibitor of Cathepsin C (also known as Dipeptidyl peptidase I) with an IC50 of 5.31 nM. DPP-1-IN-1 can inhibit the activity of Cathepsin C downstream Neutrophil elastase in neutrophils. DPP-1-IN-1 can be used in the research of inflammatory diseases[1].
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DPP-1-IN-1 | DPP-1-IN-1 (Compound 14) is an orally active inhibitor of Cathepsin C (also known as Dipeptidyl peptidase I) with an IC50 of 5.31 nM. DPP-1-IN-1 can inhibit the activity of Cathepsin C downstream Neutrophil elastase in neutrophils. DPP-1-IN-1 can be used in the research of inflammatory diseases. | |||||||||||||||||||||
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