2785430-86-4
2785430-86-4
Chemical Structure
ALK5-IN-30
- CAS No.: 2785430-86-4
- Formula:C24H25FN8
- Molecular Weight:444.51
IUPAC Name: N4-(6-fluoro-8-methylcinnolin-4-yl)-N2-(4-(4-methylpiperazin-1-yl)phenyl)pyrimidine-2,4-diamine
InChIKey: CDHXGEMVDNDKPE-UHFFFAOYSA-N
SMILES: CN1CCN(C2=CC=C(NC3=NC=CC(NC4=C5C=C(F)C=C(C)C5=NN=C4)=N3)C=C2)CC1
Biological Activity: ALK5-IN-30 (EX-07) is a potent ALK inhibitor, inhibits ALK5 and TGFβ-R1 with both IC50s <10 nM[1].
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ALK5-IN-30 | ALK5-IN-30 (EX-07) is a potent ALK inhibitor, inhibits ALK5 and TGFβ-R1 with both IC50s <10 nM. | |||||||||||||||||||||
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References
Keywords
