2789711-47-1
2789711-47-1
Chemical Structure
Dyrk1A/α-synuclein-IN-1
- CAS No.: 2789711-47-1
- Formula:C20H21N5O3S
- Molecular Weight:411.48
IUPAC Name: N-(4-(3-(6-hydroxybenzo[d]thiazol-2-yl)ureido)phenyl)piperidine-4-carboxamide
InChIKey: ATNNUKBJZFOVTK-UHFFFAOYSA-N
SMILES: O=C(NC1=NC2=C(S1)C=C(C=C2)O)NC3=CC=C(C=C3)NC(C4CCNCC4)=O
Biological Activity: Dyrk1A/α-synuclein-IN-1 (Compound b1) is a dual Dyrk1A and α-synuclein aggregation inhibitor with IC50 values of 177 nM and 10.5 µM, respectively. Dyrk1A/α-synuclein-IN-1 has high predictive CNS penetration and neuroprotective effect[1].
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Dyrk1A/α-synuclein-IN-1 | Dyrk1A/α-synuclein-IN-1 (Compound b1) is a dual Dyrk1A and α-synuclein aggregation inhibitor with IC50 values of 177 nM and 10.5 µM, respectively. Dyrk1A/α-synuclein-IN-1 has high predictive CNS penetration and neuroprotective effect. | |||||||||||||||||||||
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References
Keywords
