2802453-88-7
2802453-88-7
Chemical Structure
SHP2-IN-22
- CAS No.: 2802453-88-7
- Formula:C23H22Cl2N8O
- Molecular Weight:497.38
InChIKey: MZIJBZJSXSVRKO-UHFFFAOYSA-N
SMILES: N/C(N1CCN(CC1)C2=CN=C(C(N)=N2)C3=CC=CC(Cl)=C3Cl)=N\C4=CC(OC)=C(C=C4)C#N
Biological Activity: SHP2-IN-22 is SHP2 allosteric inhibitor with an IC50 value of 17.7 nM. SHP2-IN-22 inhibits the proliferation, migration, and invasion of MIA PaCa-2 pancreatic cancer cells. SHP2-IN-22 can be used for Kirsten rat sarcoma viral oncogene (KRAS) mutant cancer research[1].
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SHP2-IN-22 | SHP2-IN-22 is SHP2 allosteric inhibitor with an IC50 value of 17.7 nM. SHP2-IN-22 inhibits the proliferation, migration, and invasion of MIA PaCa-2 pancreatic cancer cells. SHP2-IN-22 can be used for Kirsten rat sarcoma viral oncogene (KRAS) mutant cancer research. | |||||||||||||||||||||
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References
Keywords
