2820426-92-2
2820426-92-2
Chemical Structure
BTK-IN-15
- CAS No.: 2820426-92-2
- Formula:C28H24FN5O2
- Molecular Weight:481.52
IUPAC Name: N-(4-(5-(1-acryloyl-1,2,3,6-tetrahydropyridin-4-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-2-fluorobenzyl)benzamide
InChIKey: MLZFQUIEECNEMP-UHFFFAOYSA-N
SMILES: O=C(C=C)N1CCC(C2=CNC3=NC=NC(C4=CC=C(CNC(C5=CC=CC=C5)=O)C(F)=C4)=C23)=CC1
Biological Activity: BTK-IN-15 (compound 42) is a potent Bruton's tyrosine kinase (BTK) inhibitor with high oral absorption. BTK-IN-15 inhibits BTK with an IC50 value of 0.7 nM. BTK-IN-15 displays excellent kinase selectivity, antitumor activity, and induces apoptosis[1].
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BTK-IN-15 | BTK-IN-15 (compound 42) is a potent Bruton's tyrosine kinase (BTK) inhibitor with high oral absorption. BTK-IN-15 inhibits BTK with an IC50 value of 0.7 nM. BTK-IN-15 displays excellent kinase selectivity, antitumor activity, and induces apoptosis. | |||||||||||||||||||||
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References
Keywords
