2824922-28-1

BTK-IN-8 Chemical Structure
2824922-28-1

Chemical Structure

BTK-IN-8

  • CAS No.: 2824922-28-1
  • Formula:C26H36N6O3
  • Molecular Weight:480.60

IUPAC Name: N-(2-((4-amino-6-(4-((4-isobutyl-2-oxopiperazin-1-yl)methyl)-3-methylphenyl)pyrimidin-5-yl)oxy)ethyl)-N-methylacrylamide

InChIKey: HGYLDYXQKAISMX-UHFFFAOYSA-N

SMILES: CC(C)CN(CC1=O)CCN1CC(C(C)=C2)=CC=C2C(N=CN=C3N)=C3OCCN(C)C(C=C)=O

Biological Activity: BTK-IN-8 is a potent and selective peripheral covalent BTK inhibitor (IC50=0.22 nM; Kd=0.91 nM). BTK-IN-8 has good whole blood CD69 cellular potency (IC50=0.029 µM)[1].

Cat. No. Product Name Purity Description Pricing
HY-145884 		BTK-IN-8 BTK-IN-8 is a potent and selective peripheral covalent BTK inhibitor (IC50=0.22 nM; Kd=0.91 nM). BTK-IN-8 has good whole blood CD69 cellular potency (IC50=0.029 µM).
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