2845153-35-5

Polfurmetinib hydrate Chemical Structure
2845153-35-5

Chemical Structure

Polfurmetinib hydrate

Synonym(s): MEK-IN-6 hydrate

  • CAS No.: 2845153-35-5
  • Formula:C18H22FN3O5S
  • Molecular Weight:411.45

IUPAC Name: 8-((2-fluoro-4-(methylthio)phenyl)amino)-2-(2-hydroxyethoxy)-7-methyl-3,4-dihydro-2,7-naphthyridine-1,6(2H,7H)-dione hydrate

InChIKey: CDXHDFBWQJOMDO-UHFFFAOYSA-N

SMILES: O=C1C=C2C(C(N(CC2)OCCO)=O)=C(N1C)NC3=CC=C(C=C3F)SC.O

Biological Activity: Polfurmetinib (MEK-IN-6) hydrate (compound 69) is a MEK inhibitor. Polfurmetinib hydrate has an IC50 of 2 nM for A375 cells[1].

Cat. No. Product Name Purity Description Pricing
HY-153445A
Polfurmetinib hydrate Polfurmetinib (MEK-IN-6) hydrate (compound 69) is a MEK inhibitor. Polfurmetinib hydrate has an IC50 of 2 nM for A375 cells.
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