2857033-34-0
2857033-34-0
Chemical Structure
EGFR-IN-73
- CAS No.: 2857033-34-0
- Formula:C19H17ClFN3O4
- Molecular Weight:405.81
IUPAC Name: 35-chloro-34-fluoro-17-methoxy-4,7,10-trioxa-2-aza-1(4,6)-quinazolina-3(1,2)-benzenacyclodecaphane
InChIKey: AUQWYJACINWNEL-UHFFFAOYSA-N
SMILES: COC1=C2C=C(C(NC3=CC(Cl)=C(F)C=C3OCCOCCO2)=NC=N4)C4=C1
Biological Activity: EGFR-IN-73 (Compound 3f) is a potent inhibitor for the most common EGFR mutation EGFR Del19 with an IC50 of 119 nM[1].
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EGFR-IN-73 | EGFR-IN-73 (Compound 3f) is a potent inhibitor for the most common EGFR mutation EGFR Del19 with an IC50 of 119 nM. | |||||||||||||||||||||
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References
Keywords
