2870696-46-9
2870696-46-9
Chemical Structure
Axl-IN-19
- CAS No.: 2870696-46-9
- Formula:C31H33N5O2
- Molecular Weight:507.63
SMILES: CN(C(C1=CC=C(C=C1)C2=NNC3=NC=C(C=C32)C4=CC=C5CC[C@@H](CCC5=C4)N6C7COCC6C7)=O)C
Biological Activity: Axl-IN-19 (Compound 68) is a selective AXL (a membrane-bound receptor tyrosine kinase) inhibitor (IC50: 5.3 nM; Cellular KD = 6.8 nM). Axl-IN-19 has favorable rat PK with low clearance and moderate bioavailability. Axl-IN-19 can be used for cancer research[1].
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Axl-IN-19 | Axl-IN-19 (Compound 68) is a selective AXL (a membrane-bound receptor tyrosine kinase) inhibitor (IC50: 5.3 nM; Cellular KD = 6.8 nM). Axl-IN-19 has favorable rat PK with low clearance and moderate bioavailability. Axl-IN-19 can be used for cancer research. | |||||||||||||||||||||
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References
Keywords
