Axl-IN-19
Axl-IN-19 (Compound 68) is a selective AXL (a membrane-bound receptor tyrosine kinase) inhibitor (IC50: 5.3 nM; Cellular KD = 6.8 nM). Axl-IN-19 has favorable rat PK with low clearance and moderate bioavailability. Axl-IN-19 can be used for cancer research.
For research use only. We do not sell to patients.
- CAS No.: 2870696-46-9
- Formula: C31H33N5O2
- Molecular Weight:507.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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Axl 5.3 nM (IC50) |
Chemical Information
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CAS No. 2870696-46-9
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Molecular Weight 507.63
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Formula C31H33N5O2
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SMILES
CN(C(C1=CC=C(C=C1)C2=NNC3=NC=C(C=C32)C4=CC=C5CC[C@@H](CCC5=C4)N6C7COCC6C7)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)