2876-08-6
2876-08-6
Chemical Structure
1,2-Dimethylbenzimidazole
- CAS. Nr.: 2876-08-6
- Formula:C9H10N2
- Molecular Weight:146.19
IUPAC Name: 1,2-dimethyl-1H-benzo[d]imidazole
InChIKey: PJQIBTFOXWGAEN-UHFFFAOYSA-N
SMILES: CC1=NC2=C(N1C)C=CC=C2
Biological Activity: 1,2-Dimethylbenzimidazole is a benzimidazole derivative. 1,2-Dimethylbenzimidazole exhibits antiparasitic activity with an IC50 of 0.089 μM against G. duodenalis. 1,2-Dimethylbenzimidazole can also be used in the synthesis of other bioactive compounds, such as antitumor agents[1][2].
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1,2-Dimethylbenzimidazole | 98.0% | 1,2-Dimethylbenzimidazole is a benzimidazole derivative. 1,2-Dimethylbenzimidazole exhibits antiparasitic activity with an IC50 of 0.089 μM against G. duodenalis. 1,2-Dimethylbenzimidazole can also be used in the synthesis of other bioactive compounds, such as antitumor agents. | ||||||||||||||||||||
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References
- [1]. Hernández-Covarrubias C, et al. Exploring the interplay of physicochemical properties, membrane permeability and giardicidal activity of some benzimidazole derivatives. Eur J Med Chem. 2012 Jun;52:193-204. [Content Brief]
- [2]. Gümüş F, et al. Synthesis, cytotoxic activity on MCF-7 cell line and mutagenic activity of platinum(II) complexes with 2-substituted benzimidazole ligands. Eur J Med Chem. 2003 May;38(5):473-80. [Content Brief]
