2883232-92-4
2883232-92-4
Chemical Structure
BTK-IN-16
- CAS No.: 2883232-92-4
- Formula:C15H14N4O2
- Molecular Weight:282.30
IUPAC Name: 6,7-dimethoxy-N-(pyridin-3-yl)quinazolin-4-amine
InChIKey: UWUDVFRBAXYEPH-UHFFFAOYSA-N
SMILES: COC1=CC(C(C=C1OC)=NC=N2)=C2NC3=CC=CN=C3
Biological Activity: BTK-IN-16 is a dual inhibitor of BTK wild type and C481S mutant of Bruton’s tyrosine kinase (BTK) with IC50s of 5.1 and 4.1 μM. BTK-IN-16 can be used for the research of autoimmune diseases and chronic lymphocytic leukemia[1].
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BTK-IN-16 | 98.93% | BTK-IN-16 is a dual inhibitor of BTK wild type and C481S mutant of Bruton’s tyrosine kinase (BTK) with IC50s of 5.1 and 4.1 μM. BTK-IN-16 can be used for the research of autoimmune diseases and chronic lymphocytic leukemia. | ||||||||||||||||||||
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References
Keywords
