2883498-73-3
2883498-73-3
Chemical Structure
ZL-Pin13
- CAS No.: 2883498-73-3
- Formula:C24H23ClN2O3S
- Molecular Weight:454.97
IUPAC Name: 8-(2-chloroacetyl)-4-((5-(naphthalen-1-yl)furan-2-yl)methyl)-1-thia-4,8-diazaspiro[4.5]decan-3-one
InChIKey: CQONNOYAHGRTDI-UHFFFAOYSA-N
SMILES: O=C(CSC12CCN(CC2)C(CCl)=O)N1CC3=CC=C(O3)C4=CC=CC5=C4C=CC=C5
Biological Activity: ZL-Pin13 is a high potent cell-active covalent inhibitor targeting the Pin1 (Peptidyl-Prolyl Isomerase NIMA-Interacting-1) with an IC50 of 67 nM. ZL-Pin13 effectively inhibits the proliferation and downregulated the Pin1 substrates in MDA-MB-231 cells[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ZL-Pin13 | 99.87% | ZL-Pin13 is a high potent cell-active covalent inhibitor targeting the Pin1 (Peptidyl-Prolyl Isomerase NIMA-Interacting-1) with an IC50 of 67 nM. ZL-Pin13 effectively inhibits the proliferation and downregulated the Pin1 substrates in MDA-MB-231 cells. | ||||||||||||||||||||
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References
Keywords
