2883627-63-0
Chemical Structure
α-Synuclein-IN-22
- CAS No.: 2883627-63-0
- Formula:C22H18N2O5
- Molecular Weight:390.39
InChIKey: VDVKBWZCWJLHNQ-KGVSQERTSA-N
SMILES: O=C(C1=CC=C(C=C1)O)NC2=CC=C(C=C2)NC(/C=C/C3=C(C=CC(O)=C3)O)=O
Biological Activity: α-Synuclein-IN-22 is an α-Synuclein inhibitor with an IC50 of 2.7 μM against human α-Syn. α-Synuclein-IN-22 exerts anti-aggregation effects by stabilizing the native conformation of α-Syn, inhibiting the formation of β-sheet aggregates and inclusion bodies, and dissociating mature fibrils into functional monomers. α-Synuclein-IN-22 scavenges ROS and shows low cytotoxicity. α-Synuclein-IN-22 can be used in research related to Parkinson's disease[1].
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α-Synuclein-IN-22 | α-Synuclein-IN-22 is an α-Synuclein inhibitor with an IC50 of 2.7 μM against human α-Syn. α-Synuclein-IN-22 exerts anti-aggregation effects by stabilizing the native conformation of α-Syn, inhibiting the formation of β-sheet aggregates and inclusion bodies, and dissociating mature fibrils into functional monomers. α-Synuclein-IN-22 scavenges ROS and shows low cytotoxicity. α-Synuclein-IN-22 can be used in research related to Parkinson's disease. | |||||||||||||||||||||
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Keywords
