2897695-26-8
2897695-26-8
Chemical Structure
ACLY-IN-1
- CAS No.: 2897695-26-8
- Formula:C20H12BrClF2N2O4S
- Molecular Weight:529.74
InChIKey: RKZVPLLJIUJHJX-UHFFFAOYSA-N
SMILES: ClC1=CC2=CC(S(=O)(NC3=CC(C4=C(C=CC(Br)=C4)CNC2=O)=C(C=C3F)F)=O)=C1O
Biological Activity: ACLY-IN-1 is an orally active ACLY inhibitor. ACLY-IN-1 exhibits potent ACLY inhibitory activity (IC50 = 8.3 nM) and high binding affinity (KD = 72.0 nM) to ACLY. ACLY-IN-1 demonstrates good pharmacokinetic profiles and a potent in vivo hypolipidemic effect[1].
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ACLY-IN-1 | ACLY-IN-1 is an orally active ACLY inhibitor. ACLY-IN-1 exhibits potent ACLY inhibitory activity (IC50 = 8.3 nM) and high binding affinity (KD = 72.0 nM) to ACLY. ACLY-IN-1 demonstrates good pharmacokinetic profiles and a potent in vivo hypolipidemic effect. | |||||||||||||||||||||
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References
Keywords
