2911585-60-7
2911585-60-7
Chemical Structure
LSD1-IN-25
- CAS No.: 2911585-60-7
- Formula:C32H33ClN6O3S
- Molecular Weight:617.16
IUPAC Name: (1S,2R)-N-(4-((3-(3-chlorobenzyl)-5-(propylthio)-3H-[1,2,3]triazolo[4,5-d]pyrimidin-7-yl)oxy)-3,5-dimethoxybenzyl)-2-phenylcyclopropan-1-amine
InChIKey: GTPVAJXOALUVNI-RPBOFIJWSA-N
SMILES: ClC1=CC=CC(CN2C(N=C(SCCC)N=C3OC4=C(OC)C=C(CN[C@H]5C[C@@H]5C6=CC=CC=C6)C=C4OC)=C3N=N2)=C1
Biological Activity: LSD1-IN-25 (Compound 9j) is a potent, selective and orally active LSD1 inhibitor with an IC50 of 46 nM (Ki = 30.3 nM). LSD1-IN-25 induces cancer cell apoptosis[1].
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LSD1-IN-25 | LSD1-IN-25 (Compound 9j) is a potent, selective and orally active LSD1 inhibitor with an IC50 of 46 nM (Ki = 30.3 nM). LSD1-IN-25 induces cancer cell apoptosis. | |||||||||||||||||||||
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References
Keywords
