2915618-92-5
2915618-92-5
Chemical Structure
(rac)-K20
- CAS No.: 2915618-92-5
- Formula:C24H20Cl2F4N4O2
- Molecular Weight:543.34
IUPAC Name: 1-(4-(6-chloro-7-(5-chloro-2-methoxyphenyl)-8-fluoroquinazolin-4-yl)-3-methylpiperazin-1-yl)-2-(trifluoromethyl)prop-2-en-1-one
InChIKey: YNPOWLWDWOTQIZ-UHFFFAOYSA-N
SMILES: C=C(C(N1CCN(C(C1)C)C2=NC=NC3=C(C(C4=CC(Cl)=CC=C4OC)=C(C=C23)Cl)F)=O)C(F)(F)F
Biological Activity: (rac)-K20 is the racemate of K20, a KRas G12C inhibitor with an IC50 of 1.16 μM. K20 has antitumor activity[1].
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(rac)-K20 | (rac)-K20 is the racemate of K20, a KRas G12C inhibitor with an IC50 of 1.16 μM. K20 has antitumor activity. | |||||||||||||||||||||
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References
Keywords
