2925070-64-8
Chemical Structure
CRBN ligand-461
- CAS No.: 2925070-64-8
- Formula:C13H10N4O3
- Molecular Weight:270.25
IUPAC Name: 8-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)quinazoline-4-carbaldehyde
InChIKey: RJYVPAGYVIOGRZ-UHFFFAOYSA-N
SMILES: O=CC1=NC=NC2=C1C=CC=C2N3C(=O)NC(=O)CC3
Biological Activity: CRBN ligand-461 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-461 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-461 | CRBN ligand-461 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-461 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords