2925081-80-5
Chemical Structure
CRBN ligand-744
- CAS No.: 2925081-80-5
- Formula:C14H13N3O4
- Molecular Weight:287.28
IUPAC Name: 6-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-1-methyl-1H-indole-2-carboxylic acid
InChIKey: ORJCPJYEZGRSKW-UHFFFAOYSA-N
SMILES: O=C(O)C1=CC=2C=CC(=CC2N1C)N3C(=O)NC(=O)CC3
Biological Activity: CRBN ligand-744 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-744 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-744 | CRBN ligand-744 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-744 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords