2925085-71-6
Chemical Structure
CRBN ligand-727
- CAS No.: 2925085-71-6
- Formula:C13H12N4O3
- Molecular Weight:272.26
IUPAC Name: 4-(2,4-dioxotetrahydropyrimidin-1(2H)-yl)-1-methyl-1H-indazole-6-carbaldehyde
InChIKey: PHJGKXLVOUSPJJ-UHFFFAOYSA-N
SMILES: O=CC=1C=C2C(C=NN2C)=C(C1)N3C(=O)NC(=O)CC3
Biological Activity: CRBN ligand-727 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-727 can be linked to a target protein ligand via a linker to form a PROTAC.
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CRBN ligand-727 | CRBN ligand-727 is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. CRBN ligand-727 can be linked to a target protein ligand via a linker to form a PROTAC. | |||||||||||||||||||||
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Keywords