2935903-77-6
2935903-77-6
Chemical Structure
HPK1-IN-35
- CAS No.: 2935903-77-6
- Formula:C30H32N8O3S
- Molecular Weight:584.69
IUPAC Name: 2-((2-((6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino)-5-(pyridin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-N,N-dimethylbenzenesulfonamide
InChIKey: UVFANRIFEXGNPK-UHFFFAOYSA-N
SMILES: COC1=C(C=C2CN(CCC2=C1)C)NC3=NC4=C(C(NC5=CC=CC=C5S(=O)(N(C)C)=O)=N3)C(C6=CC=CN=C6)=CN4
Biological Activity: HPK1-IN-35 is a potent and selective HPK1 inhibitor with an IC50 value of 3.5 nM. HPK1-IN-35 decreases the expression of p-SLP76 and promotes IL-2 secretion[1].
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HPK1-IN-35 | HPK1-IN-35 is a potent and selective HPK1 inhibitor with an IC50 value of 3.5 nM. HPK1-IN-35 decreases the expression of p-SLP76 and promotes IL-2 secretion. | |||||||||||||||||||||
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References
Keywords
