2940248-11-1
2940248-11-1
Chemical Structure
ATX inhibitor 26
- CAS No.: 2940248-11-1
- Formula:C18H19Cl2N7O3
- Molecular Weight:452.29
InChIKey: LMCWDXBBYKLXFJ-UHFFFAOYSA-N
SMILES: ClC1=CC(Cl)=CC(COC(N2CCC(C3=NN=C(NCC4=CN=NN4)O3)CC2)=O)=C1
Biological Activity: ATX inhibitor 26 is an Autotaxin (ATX) inhibitor with an IC50 of 57 nM in human plasma. ATX inhibitor 26 inhibits cell migration and collagen gel contraction. ATX inhibitor 26 has significant anti-fibrotic effects, reducing collagen deposition in a Bleomycin (BLM) (HY-108345)-induced pulmonary fibrosis model[1].
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ATX inhibitor 26 | ATX inhibitor 26 is an Autotaxin (ATX) inhibitor with an IC50 of 57 nM in human plasma. ATX inhibitor 26 inhibits cell migration and collagen gel contraction. ATX inhibitor 26 has significant anti-fibrotic effects, reducing collagen deposition in a Bleomycin (BLM) (HY-108345)-induced pulmonary fibrosis model. | |||||||||||||||||||||
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References
Keywords
