2941026-35-1
2941026-35-1
Chemical Structure
c-Kit-IN-7
- CAS 番号: 2941026-35-1
- Formula:C27H32FN7O3
- Molecular Weight:521.59
SMILES: CC(C#N)(CCNC(NC1=CC=C(C=C1)NC2=NC=NC3=CC(OCCN4CCOCC4)=CC(F)=C32)=O)C
Biological Activity: c-Kit-IN-7 (Compound 104) is a potent inhibitor of c-Kit, with IC50 values of ≤10 nM. c-Kit-IN-7 inhibits the cell proliferation in GIST430 and BaF3 mutants, with IC50 values of ≤100 nM. c-Kit-IN-7 plays an important role in cancer driven by c-KIT kinase mutations research[1].
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c-Kit-IN-7 | c-Kit-IN-7 (Compound 104) is a potent inhibitor of c-Kit, with IC50 values of ≤10 nM. c-Kit-IN-7 inhibits the cell proliferation in GIST430 and BaF3 mutants, with IC50 values of ≤100 nM. c-Kit-IN-7 plays an important role in cancer driven by c-KIT kinase mutations research. | |||||||||||||||||||||
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