2947393-64-6
Chemical Structure
NNMT-IN-4
- CAS No.: 2947393-64-6
- Formula:C9H11N3O
- Molecular Weight:177.20
IUPAC Name: (R)-2-methyl-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-5-carboxamide
InChIKey: HLBSXLCCTVSVBK-RXMQYKEDSA-N
SMILES: C[C@@H]1CC2=C(N1)N=CC(C(N)=O)=C2
Biological Activity: NNMT-IN-4 (compound 38) is a selective, uncompetitive and membrane permeability nicotinamide N-methyltransferase (NNMT) inhibitor with IC50 values of 42 and 38 nM in vitro biochemical and cell-based assays, respectively. NNMT-IN-4 shows favorable PK/PD and safety profiles as well as excellent oral bioavailability and pharmaceutical properties. NNMT-IN-4 can be used as a vivo chemical probe of NNMT[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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NNMT-IN-4 | 99.35% | NNMT-IN-4 (compound 38) is a selective, uncompetitive and membrane permeability nicotinamide N-methyltransferase (NNMT) inhibitor with IC50 values of 42 and 38 nM in vitro biochemical and cell-based assays, respectively. NNMT-IN-4 shows favorable PK/PD and safety profiles as well as excellent oral bioavailability and pharmaceutical properties. NNMT-IN-4 can be used as a vivo chemical probe of NNMT. | ||||||||||||||||||||
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Keywords
