2951090-00-7
Chemical Structure
SIRT5 inhibitor 7
- CAS No.: 2951090-00-7
- Formula:C28H32ClN7O3S
- Molecular Weight:582.12
InChIKey: YVUGRSDTNXBWNT-FQEVSTJZSA-N
SMILES: S=C(NCCCNC1=NC(NC2=C(Cl)C=CC=C2)=NC=C1C(N3C[C@@H](C4=CC=CC=C4)CC3)=O)NCCC(O)=O
Biological Activity: SIRT5 inhibitor 7 (compound 58) is a substrate-competitive and selective SIRT5 inhibitor with anti-inflammatory activity. SIRT5 inhibitor 7 has renal protective effects and regulates protein succinylation and the release of pro-inflammatory cytokines. SIRT5 inhibitor 7 has in vivo activity in AKI mouse models of lipopolysaccharide (LPS) and cecal ligation/perforation (CLP)-induced sepsis-related acute kidney injury[1].
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SIRT5 inhibitor 7 | 99.66% | SIRT5 inhibitor 7 (compound 58) is a substrate-competitive and selective SIRT5 inhibitor with anti-inflammatory activity. SIRT5 inhibitor 7 has renal protective effects and regulates protein succinylation and the release of pro-inflammatory cytokines. SIRT5 inhibitor 7 has in vivo activity in AKI mouse models of lipopolysaccharide (LPS) and cecal ligation/perforation (CLP)-induced sepsis-related acute kidney injury. | ||||||||||||||||||||
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Keywords
