2976497-48-8
2976497-48-8
Chemical Structure
PARP-1-IN-23
- CAS No.: 2976497-48-8
- Formula:C22H18BrN3O5S
- Molecular Weight:516.36
InChIKey: FWZXLBLAODSAKH-UHFFFAOYSA-N
SMILES: BrC1=CC(C2=NC3=C(C=CC=C3N2)C(N)=O)=CC(OC)=C1OS(=O)(C4=CC=CC=C4C)=O
Biological Activity: PARP-1-IN-23 (Compound I16 ) is an orally active and selective PARP-1 inhibitor with the IC50 of 12.38 nM. PARP-1-IN-23 inhibits tumor growth in vivo[1].
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PARP-1-IN-23 | PARP-1-IN-23 (Compound I16 ) is an orally active and selective PARP-1 inhibitor with the IC50 of 12.38 nM. PARP-1-IN-23 inhibits tumor growth in vivo. | |||||||||||||||||||||
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References
Keywords
