2983027-64-9

CBP/p300-IN-18 Chemical Structure
2983027-64-9

Chemical Structure

CBP/p300-IN-18

  • CAS No.: 2983027-64-9
  • Formula:C25H27FN4O3
  • Molecular Weight:450.51

IUPAC Name: (2R,4R)-4-fluoro-N-(1H-indazol-4-yl)-1-(1-(4-methoxyphenyl)cyclopentane-1-carbonyl)pyrrolidine-2-carboxamide

InChIKey: FLUJAHQWJJQENP-VGOFRKELSA-N

SMILES: O=C([C@@H]1N(C(C2(C3=CC=C(OC)C=C3)CCCC2)=O)C[C@H](F)C1)NC4=CC=CC5=C4C=NN5

Biological Activity: CBP/p300-IN-18 (compound 8) is a potent EP300/CBP HAT inhibitor with IC50s of 0.056, 0.46 µM for HAT EP300 and LK2 H3K27, respectively[1].

Cat. No. Product Name Purity Description Pricing
HY-143442 		CBP/p300-IN-18 CBP/p300-IN-18 (compound 8) is a potent EP300/CBP HAT inhibitor with IC50s of 0.056, 0.46 µM for HAT EP300 and LK2 H3K27, respectively.
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