3024381-54-9

CDK8/19-IN-2 Chemical Structure
3024381-54-9

Chemical Structure

CDK8/19-IN-2

  • CAS No.: 3024381-54-9
  • Formula:C17H20Br2F2N4O
  • Molecular Weight:494.17

InChIKey: YRFOQHHFWYWAST-UHFFFAOYSA-N

SMILES: BrC1=C(C=C2N(C(N3CCNCC3)=NC2=C1C(F)F)C4CCOCC4)Br

Biological Activity: CDK8/19-IN-2 (compound 12) is an orally active and potent cyclin-dependent kinase 8/19 (CDK8 and CDK19) inhibitor, with IC50 values of 2.08 and 2.49 nM, respectively. CDK8/19-IN-2 can be used for acute myeloid leukemia (AML), breast cancer, and lymphoma research[1].

Cat. No. Product Name Purity Description Pricing
HY-158377 		CDK8/19-IN-2 CDK8/19-IN-2 (compound 12) is an orally active and potent cyclin-dependent kinase 8/19 (CDK8 and CDK19) inhibitor, with IC50 values of 2.08 and 2.49 nM, respectively. CDK8/19-IN-2 can be used for acute myeloid leukemia (AML), breast cancer, and lymphoma research.
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