3024723-74-5
3024723-74-5
Chemical Structure
CDK12-IN-9
- CAS No.: 3024723-74-5
- Formula:C23H20F2N10
- Molecular Weight:474.47
InChIKey: YQCFBWLXNKEACR-MSOLQXFVSA-N
SMILES: N#CC1=CC2=C(N(C=N2)[C@H]3CCC[C@H](C3)NC4=NC=C(C(C5=CN(N=C5)CC(F)F)=N4)C#N)N=C1
Biological Activity: CDK12-IN-9 is a potent and selective CDK12 inhibitor with an IC50 of 2.2 nM. CDK12-IN-9 inhibits pSER2 (a downstream marker of CDK12/13 activity). CDK12-IN-9 can be used for the research of cancer[1].
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CDK12-IN-9 | CDK12-IN-9 is a potent and selective CDK12 inhibitor with an IC50 of 2.2 nM. CDK12-IN-9 inhibits pSER2 (a downstream marker of CDK12/13 activity). CDK12-IN-9 can be used for the research of cancer. | |||||||||||||||||||||
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References
Keywords
