3026670-71-0
Chemical Structure
Pim-1 kinase inhibitor 4
- CAS No.: 3026670-71-0
- Formula:C19H12ClN3O
- Molecular Weight:333.77
IUPAC Name: 2-(3-chlorophenyl)-5-(2-phenylpyridin-4-yl)-1,3,4-oxadiazole
InChIKey: SRYWKHYHULAEMS-UHFFFAOYSA-N
SMILES: ClC1=CC(C2=NN=C(O2)C3=CC=NC(C4=CC=CC=C4)=C3)=CC=C1
Biological Activity: Pim-1 kinase inhibitor 4 (Compound 10f) is a Pim-1 kinase inhibitor (IC50: 17.01 nM). Pim-1 kinase inhibitor 4 also has antioxidant activity and inhibits DPPH. Pim-1 kinase inhibitor 4 induces apoptosis in PC-3 cell, and inhibits PC-3 cell growth with an IC50 of 16 nM. Pim-1 kinase inhibitor 4 can be used for research of prostate cancer[1].
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Pim-1 kinase inhibitor 4 | Pim-1 kinase inhibitor 4 (Compound 10f) is a Pim-1 kinase inhibitor (IC50: 17.01 nM). Pim-1 kinase inhibitor 4 also has antioxidant activity and inhibits DPPH. Pim-1 kinase inhibitor 4 induces apoptosis in PC-3 cell, and inhibits PC-3 cell growth with an IC50 of 16 nM. Pim-1 kinase inhibitor 4 can be used for research of prostate cancer. | |||||||||||||||||||||
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Keywords
