3026690-49-0
3026690-49-0
Chemical Structure
MenA-IN-2
- CAS No.: 3026690-49-0
- Formula:C23H31ClN2O
- Molecular Weight:386.96
IUPAC Name: 4-((4-((4-chlorophenoxy)methyl)piperidin-1-yl)methyl)-N-methyl-N-propylaniline
InChIKey: IELKIDMEJICGCF-UHFFFAOYSA-N
SMILES: CCCN(C1=CC=C(C=C1)CN2CCC(CC2)COC3=CC=C(C=C3)Cl)C
Biological Activity: MenA-IN-2 (Compound 11) is an inhibitor of 1,4-dihydroxy-2-naphthoate prenyltransferase (MenA). MenA-IN-2 inhibits MenA with an IC50 value of 22 µM and inhibits Mycobacterium tuberculosis (Mtb) with an GIC50 value of 10 µM. MenA-IN-2 can curb the continuous transmission of Mtb[1].
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MenA-IN-2 | 99.84% | MenA-IN-2 (Compound 11) is an inhibitor of 1,4-dihydroxy-2-naphthoate prenyltransferase (MenA). MenA-IN-2 inhibits MenA with an IC50 value of 22 µM and inhibits Mycobacterium tuberculosis (Mtb) with an GIC50 value of 10 µM. MenA-IN-2 can curb the continuous transmission of Mtb. | ||||||||||||||||||||
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References
Keywords
