3026728-26-4
3026728-26-4
Chemical Structure
KDM5-C49 hydrochloride
Synonym(s): KDOAM-20 hydrochloride
- CAS No.: 3026728-26-4
- Formula:C15H25ClN4O3
- Molecular Weight:344.84
IUPAC Name: 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinic acid hydrochloride
InChIKey: OESDMKMTFUZZFE-UHFFFAOYSA-N
SMILES: O=C(C1=CC=NC(CNCC(N(CC)CCN(C)C)=O)=C1)O.[H]Cl
Biological Activity: KDM5-C49 (KDOAM-20) hydrochloride is a potent and selective inhibitor of KDM5 demethylases, with IC50s of 40 nM, 160 nM, and 100 nM for KDM5A, KDM5B, and KDM5C enzymes, respectively. KDM5-C49 hydrochloride can be used for the research of cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KDM5-C49 hydrochloride | 98.22% | KDM5-C49 (KDOAM-20) hydrochloride is a potent and selective inhibitor of KDM5 demethylases, with IC50s of 40 nM, 160 nM, and 100 nM for KDM5A, KDM5B, and KDM5C enzymes, respectively. KDM5-C49 hydrochloride can be used for the research of cancer. | ||||||||||||||||||||
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