3028594-43-3
3028594-43-3
Chemical Structure
Metallo-β-lactamase-IN-12
- CAS No.: 3028594-43-3
- Formula:C18H19NO4
- Molecular Weight:313.35
InChIKey: HCJGHMQOAVFHGV-UHFFFAOYSA-N
SMILES: O=C(ONC(CCCC1=CC=CC=C1)=O)OCC2=CC=CC=C2
Biological Activity: Metallo-β-lactamase-IN-12 is a dual inhibitor of metal β-lactamases (MβLs (NDM-1, IMP-1)) and serine β-lactamases (SβLs (OXA-48, KPC-2)), with IC50 values of 0.64 μM, 1.32 μM, 1.01 μM, and 0.57 μM, respectively. Metallo-β-lactamase-IN-12 has antibacterial activity[1].
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Metallo-β-lactamase-IN-12 | Metallo-β-lactamase-IN-12 is a dual inhibitor of metal β-lactamases (MβLs (NDM-1, IMP-1)) and serine β-lactamases (SβLs (OXA-48, KPC-2)), with IC50 values of 0.64 μM, 1.32 μM, 1.01 μM, and 0.57 μM, respectively. Metallo-β-lactamase-IN-12 has antibacterial activity. | |||||||||||||||||||||
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