3035983-65-1
Chemical Structure
ATX-1905
- CAS No.: 3035983-65-1
- Formula:C32H33D4ClFN9OS
- Molecular Weight:654.24
InChIKey: WNTHMLVQTHHVAK-MKQHWYKPSA-N
SMILES: [2H]C(Cl)(C([2H])(N1CCN(CC1)C(CN2CCN(CC2)C3=CN4C(C=C3)=NC(CC)=C4N(C5=NC(C6=CC=C(C=C6)F)=C(S5)C#N)C)=O)[2H])[2H]
Biological Activity: ATX-1905 is a positron emission tomography (PET) tracer that demonstrates good autotaxin (ATX) binding specificity and achieves semiquantification of lung ATX expression levels, which are elevated in fibrotic lungs. ATX-1905 exhibits elevated uptake in Bleomycin (HY-108345)-induced pulmonary fibrosis (BPF) lungs. ATX-1905 is promising for research of idiopathic pulmonary fibrosis (IPF)[1].
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ATX-1905 | ATX-1905 is a positron emission tomography (PET) tracer that demonstrates good autotaxin (ATX) binding specificity and achieves semiquantification of lung ATX expression levels, which are elevated in fibrotic lungs. ATX-1905 exhibits elevated uptake in Bleomycin (HY-108345)-induced pulmonary fibrosis (BPF) lungs. ATX-1905 is promising for research of idiopathic pulmonary fibrosis (IPF). | |||||||||||||||||||||
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Keywords
