3050586-22-3
Chemical Structure
Anti-MRSA agent 14
- CAS No.: 3050586-22-3
- Formula:C43H53ClN2O5S
- Molecular Weight:745.41
InChIKey: MWXPPPQCGGEATR-LBWRYPOYSA-N
SMILES: CC1(C)CC[C@]2(C(NS(C3=CC=C(Cl)C=C3)(=O)=O)=O)CC[C@@]4(C)[C@]5(C)CC[C@@]6([H])C(C)(C)C7=C(C(C=CC=C8C(O)=O)=C8N7)C[C@]6(C)[C@@]5([H])CC=C4[C@]2([H])C1
Biological Activity: Anti-MRSA agent 14 (Compound C17) has antibacterial agent against MRSA and MRSA-infected skin murine model. Anti-MRSA agent 14 is more potential than Norfloxacin (HY-B0132) against MRSA. Anti-MRSA agent 14 disrupts cell membrane and restrains metabolism. Anti-MRSA agent 14 shows antibacterial effects against S. aureus ATCC 6538, S. aureus ATCC 29213, S. epidermidis ATCC 12228, and MRSA with MIC values of 1, 2, 2, 1 μM respectively[1].
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Anti-MRSA agent 14 | Anti-MRSA agent 14 (Compound C17) has antibacterial agent against MRSA and MRSA-infected skin murine model. Anti-MRSA agent 14 is more potential than Norfloxacin (HY-B0132) against MRSA. Anti-MRSA agent 14 disrupts cell membrane and restrains metabolism. Anti-MRSA agent 14 shows antibacterial effects against S. aureus ATCC 6538, S. aureus ATCC 29213, S. epidermidis ATCC 12228, and MRSA with MIC values of 1, 2, 2, 1 μM respectively. | |||||||||||||||||||||
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Keywords
