3051552-75-8
3051552-75-8
Chemical Structure
KIF18A-IN-14
- CAS No.: 3051552-75-8
- Formula:C26H32F3N5O6S
- Molecular Weight:599.62
InChIKey: ODOJSYYGDINMHP-UHFFFAOYSA-N
SMILES: O=C1NC2=CC=CC(N3CCOC(C3)COCC4(C(F)(F)F)CCN(CC4)C5=CC(NS(=O)(CCO)=O)=CC=C15)=N2
Biological Activity: KIF18A-IN-14 (Compound Example 81) is a KIF18A inhibitor. KIF18A-IN-14 is available in two forms, EX81-A and its enantiomer EX81-B. EX81-A and EX81-B inhibit OVCAR-3 cells viability with IC50s of 0-0.01 μM and 0.01-0.1 μM, respectively. KIF18A-IN-14 can be used in tumor (e.g. colon, breast, lung) studies[1].
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KIF18A-IN-14 | KIF18A-IN-14 (Compound Example 81) is a KIF18A inhibitor. KIF18A-IN-14 is available in two forms, EX81-A and its enantiomer EX81-B. EX81-A and EX81-B inhibit OVCAR-3 cells viability with IC50s of 0-0.01 μM and 0.01-0.1 μM, respectively. KIF18A-IN-14 can be used in tumor (e.g. colon, breast, lung) studies. | |||||||||||||||||||||
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References
Keywords
