3054009-82-1
3054009-82-1
Chemical Structure
KI-CDK9d-32
- CAS No.: 3054009-82-1
- Formula:C39H45N9O4
- Molecular Weight:703.83
InChIKey: DQQMOQXMKRXELC-XMOVUWPTSA-N
SMILES: O=C(N[C@H]1C[C@H](NC2=CC(CCC)=NC3=CC=NN23)CC1)C4=CC=C(CN5CCN(C6=CC7=C(C(N(C(CC8)C(NC8=O)=O)C7)=O)C=C6)CC5)C=C4
Biological Activity: KI-CDK9d-32 is a highly selective and potent CDK9 PROTAC degrader (DC50: 0.89 nM). KI-CDK9d-32 promotes the ubiquitination and degradation of CDK9. KI-CDK9d-32 inhibits the MYC pathway and disrupts nucleolar homeostasis. KI-CDK9d-32 exhibits anticancer activity against acute lymphoblastic leukemia and pancreatic cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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KI-CDK9d-32 | 99.03% | KI-CDK9d-32 is a highly selective and potent CDK9 PROTAC degrader (DC50: 0.89 nM). KI-CDK9d-32 promotes the ubiquitination and degradation of CDK9. KI-CDK9d-32 inhibits the MYC pathway and disrupts nucleolar homeostasis. KI-CDK9d-32 exhibits anticancer activity against acute lymphoblastic leukemia and pancreatic cancer. | ||||||||||||||||||||
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References
Keywords
