3060504-66-4
Chemical Structure
GSPT1 degrader-15
- CAS No.: 3060504-66-4
- Formula:C36H29N5O7S
- Molecular Weight:675.71
InChIKey: CSBJYYCCSYHJQD-SAEPALGJSA-N
SMILES: O=C(NC1=O)CCC1N(C(C2=CC=C3)=O)CC2=C3C4=CC=CC=C4OCC(N/N=C/C5=CN(S(C6=CC=CC=C6)(=O)=O)C7=C5C=CC=C7)=O
Biological Activity: GSPT1 degrader-15 (Compound Lib-B-15O) is a potent and highly selective GSPT1 molecular gel degrader, with a DC50 of 154 nM. GSPT1 degrader-15 has almost no effect on the expression of other proteins. GSPT1 degrader-15 exhibits significant anti-proliferative activity against leukemia cells and lymphoma cells. GSPT1 degrader-15 can be used in leukemia and lymphoma research[1].
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GSPT1 degrader-15 | 95.05% | GSPT1 degrader-15 (Compound Lib-B-15O) is a potent and highly selective GSPT1 molecular gel degrader, with a DC50 of 154 nM. GSPT1 degrader-15 has almost no effect on the expression of other proteins. GSPT1 degrader-15 exhibits significant anti-proliferative activity against leukemia cells and lymphoma cells. GSPT1 degrader-15 can be used in leukemia and lymphoma research. | ||||||||||||||||||||
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Keywords
