3060519-94-7

MS8588 Chemical Structure
3060519-94-7

Chemical Structure

MS8588

  • CAS No.: 3060519-94-7
  • Formula:C45H59Cl2N9O6S
  • Molecular Weight:924.98

InChIKey: BELZBQPUGRDLCQ-JLHYYAGUSA-N

SMILES: ClC1=C(NC2=C3CN(C(CO)=O)CC2)C3=C(C4=NN(CCNC(CCCCCCCCCC(NCCC5=CC=C(N6C(CN(C(/C=C/CN(C)C)=O)CC6)=O)S5)=O)=O)C=C4)C=C1Cl

Biological Activity: MS8588 is a deubiquitinase-targeting chimera (DUBTAC) against cGAS. MS8588 induces targeted stabilization of cGAS, thereby activating downstream signaling pathways. MS8588 activates the cGAS/STING/IRF3 innate immune signaling pathway. MS8588 exhibits antitumor activity[1].

Cat. No. Product Name Purity Description Pricing
HY-162967 		MS8588 MS8588 is a deubiquitinase-targeting chimera (DUBTAC) against cGAS. MS8588 induces targeted stabilization of cGAS, thereby activating downstream signaling pathways. MS8588 activates the cGAS/STING/IRF3 innate immune signaling pathway. MS8588 exhibits antitumor activity.
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