3067202-14-3
3067202-14-3
Chemical Structure
ChREBPα/14-3-3 regulator-1
- CAS No.: 3067202-14-3
- Formula:C16H15F3NO5P
- Molecular Weight:389.26
InChIKey: CWLSIOCFRIMBMV-UHFFFAOYSA-N
SMILES: FC1=CC=CC(C(F)(F)CNC(COC2=C(P(O)(O)=O)C=CC=C2)=O)=C1
Biological Activity: ChREBPα/14-3-3 regulator-1 (Compound 43) is a selective molecular gel that can stabilize the interaction of carbohydrate response element binding protein (ChREBP) with 14-3-3 proteins (EC50: 3.8 μM). ChREBPα/14-3-3 regulator-1 effectively protects β cells from glucolipotoxicity and maintains cell function, and can be used in the study of type 2 diabetes[1].
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ChREBPα/14-3-3 regulator-1 | ChREBPα/14-3-3 regulator-1 (Compound 43) is a selective molecular gel that can stabilize the interaction of carbohydrate response element binding protein (ChREBP) with 14-3-3 proteins (EC50: 3.8 μM). ChREBPα/14-3-3 regulator-1 effectively protects β cells from glucolipotoxicity and maintains cell function, and can be used in the study of type 2 diabetes. | |||||||||||||||||||||
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References
Keywords
