3070379-34-6
3070379-34-6
Chemical Structure
ZLY025
- CAS No.: 3070379-34-6
- Formula:C15H13N3O2S
- Molecular Weight:299.35
InChIKey: VVSHIGBEBPOAEX-UHFFFAOYSA-N
SMILES: CC1=CN=C(NC(CC2=CC=C(C=C2)C3=NC=CO3)=O)S1
Biological Activity:
ZLY025 is a potent and orally active CCNK molecular glue degrader with an DC50 of 42.7 nM. ZLY025 exhibits broad-spectrum antiproliferative activity against various tumor cells with IC50 values ranging from 0.08 to 2.45 μM. ZLY025 can induce cells apoptosis and G1 phase arrest. ZLY025 can be used for the research of cancer, such as lung cancer[1].
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ZLY025 | 99.40% | ZLY025 is a potent and orally active CCNK molecular glue degrader with an DC50 of 42.7 nM. ZLY025 exhibits broad-spectrum antiproliferative activity against various tumor cells with IC50 values ranging from 0.08 to 2.45 μM. ZLY025 can induce cells apoptosis and G1 phase arrest. ZLY025 can be used for the research of cancer, such as lung cancer. |
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References
Keywords
