3083163-26-9
3083163-26-9
Chemical Structure
Romolisiran
- CAS No.: 3083163-26-9
- Formula:C514H635N203O373P52
- Molecular Weight:17235.29
SMILES: [Romolisiran]
Biological Activity: Romolisiran is a sulfotransferase 15 (CHST15) synthesis inhibitor. CHST15 is upregulated in fibrosis (lung, liver, kidney), tumor stroma and inflammation; chondroitin sulfate chains modified by its product participate in TGF-β activation, collagen cross-linking and fibroblast activation. Romolisiran can be used to study diseases associated with fibrosis/stromal modification[1].
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Romolisiran | Romolisiran is a sulfotransferase 15 (CHST15) synthesis inhibitor. CHST15 is upregulated in fibrosis (lung, liver, kidney), tumor stroma and inflammation; chondroitin sulfate chains modified by its product participate in TGF-β activation, collagen cross-linking and fibroblast activation. Romolisiran can be used to study diseases associated with fibrosis/stromal modification. | |||||||||||||||||||||
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References
Keywords
