3096122-10-7
Chemical Structure
Anti-MRSA agent 36
- CAS No.: 3096122-10-7
- Formula:C29H35BrN2O5S
- Molecular Weight:603.57
InChIKey: DDKAXNKKANQVAT-UHFFFAOYSA-N
SMILES: CCCCCCNC(C[N+]1=CC=C(SCCCCCOC2=C(O3)C(C=CC3=O)=CC4=C2OC=C4)C=C1)=O.[Br-]
Biological Activity: Anti-MRSA agent 36 (Compound III13) is an antibacterial agent with strong anti MRSA activity (MIC = 1 μg/mL). Anti-MRSA agent 36 targets phosphatidylglycerol (PG) on bacterial membranes, disrupting membrane integrity, leading to DNA leakage and increased ROS. Anti-MRSA agent 36 has advantages such as low cytotoxicity, low hemolysis, difficulty in inducing drug resistance, and good plasma stability. Anti-MRSA agent 36 can be used for the study of skin abscess and systemic infection models[1].
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Anti-MRSA agent 36 | Anti-MRSA agent 36 (Compound III13) is an antibacterial agent with strong anti MRSA activity (MIC = 1 μg/mL). Anti-MRSA agent 36 targets phosphatidylglycerol (PG) on bacterial membranes, disrupting membrane integrity, leading to DNA leakage and increased ROS. Anti-MRSA agent 36 has advantages such as low cytotoxicity, low hemolysis, difficulty in inducing drug resistance, and good plasma stability. Anti-MRSA agent 36 can be used for the study of skin abscess and systemic infection models. | |||||||||||||||||||||
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Keywords
