3104123-06-7
3104123-06-7
Chemical Structure
MLK3-IN-1
- CAS No.: 3104123-06-7
- Formula:C20H16F6N4O2S
- Molecular Weight:490.42
InChIKey: WXTXWVIOZYHNDG-UHFFFAOYSA-N
SMILES: FC(C1=CC=C(NC2=NC=C(C(F)(F)F)C(NCC3=CC=CC(S(=O)(C)=O)=C3)=N2)C=C1)(F)F
Biological Activity: MLK3-IN-1 (Compound 37) is a selective inhibitor for mixed-lineage protein kinase 3 (MLK3) with an IC50 <1 nM. MLK3-IN-1 inhibits FAK with an IC50 of 15.5 μM. MLK3-IN-1 exhibits good metabolic stability in mouse and human liver microsomes[1].
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MLK3-IN-1 | MLK3-IN-1 (Compound 37) is a selective inhibitor for mixed-lineage protein kinase 3 (MLK3) with an IC50 <1 nM. MLK3-IN-1 inhibits FAK with an IC50 of 15.5 μM. MLK3-IN-1 exhibits good metabolic stability in mouse and human liver microsomes. | |||||||||||||||||||||
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