311315-04-5
311315-04-5
Chemical Structure
AD16
- CAS 番号: 311315-04-5
- Formula:C24H20N14O3S2
- Molecular Weight:616.64
InChIKey: DVYLISKRIDMIEH-UHFFFAOYSA-N
SMILES: NN1C=NN2C(SCC(CC3=CC=C(C=C3)C4=NC5=CC(NC(CSC6=NN=C7N(C=NN67)N)=O)=CC=C5O4)=O)=NN=C12
Biological Activity: AD16 (Acetamide) is a LINE-1 retrotransposon endonuclease inhibitor with the IC50 of 4.7 μM. AD16 (Acetamide) reduce LINE-1 retrotransposition, L1-induced DNA damage, and inflammation reinforced by L1 in senescent cells[1].
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AD16 | AD16 (Acetamide) is a LINE-1 retrotransposon endonuclease inhibitor with the IC50 of 4.7 μM. AD16 (Acetamide) reduce LINE-1 retrotransposition, L1-induced DNA damage, and inflammation reinforced by L1 in senescent cells. | |||||||||||||||||||||
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